Towards fostering the role of 5G networks in the field of digital health

A typical healthcare system needs further participation with patient monitoring, vital signs sensors and other medical devices. Healthcare moved from a traditional central hospital to scattered patients. Healthcare systems receive help from emerging technology innovations such as fifth generation (5G) communication infrastructure: internet of things (IoT), machine learning (ML), and artificial intelligence (AI). Healthcare providers benefit from IoT capabilities to comfort patients by using smart appliances that improve the healthcare level they receive. These IoT smart healthcare gadgets produce massive data volume. It is crucial to use very high-speed communication networks such as 5G wireless technology with the increased communication bandwidth, data transmission efficiency and reduced communication delay and latency, thus leading to strengthen the precise requirements of healthcare big data utilities. The adaptation of 5G in smart healthcare networks allows increasing number of IoT devices that supplies an augmentation in network performance. This paper reviewed distinctive aspects of internet of medical things (IoMT) and 5G architectures with their future and present sides, which can lead to improve healthcare of patients in the near future

Developments and Clinical Applications of Biomimetic Tissue Regeneration using 3D Bioprinting Technique

Tissue engineers have made great strides in the past decade thanks to the advent of three-dimensional (3D) bioprinting technology, which has allowed them to create highly customized biological structures with precise geometric design ability, allowing us to close the gap between manufactured and natural tissues. In this work, we first survey the state-of-the-art methods, cells, and materials for 3D bioprinting. The modern uses of this method in tissue engineering are then briefly discussed. Following this, the main benefits of 3D bioprinting in tissue engineering are outlined in depth, including the ability to rapidly prototype the individualized structure and the ability to engineer with a highly controllable microenvironment. Finally, we offer some predictions for the future of 3D bioprinting in the field of tissue engineering

Recent Biomaterial Developments for Bone Tissue Engineering and Potential Clinical Application: Narrative Review of the Literature

Over the course of time, there has been a progression in the materials utilized for implants, transitioning from inert substances to those that replicate the structural characteristics of bone. Consequently, there has been a development of bioabsorbable, biocompatible, and bioactive materials. This article presents a comprehensive survey of diverse biomaterials with the potential to serve as scaffolds for bone tissue engineering. The objective of this study is to present an in-depth review of the predominant biomaterials utilized in the fabrication of scaffolds. This review encompasses the origins, classifications, characteristics, and methodologies involved in the development of these biomaterials. The review also highlights the incorporation of additives in biomaterial scaffolds. This study ultimately underscores the potential advantages and challenges associated with the utilization of biomaterials in scaffolds for bone tissue engineering. Additionally, it critically examines the integration of state-of-the-art technology with biomaterials

The Evolution and Reliability of Machine Learning Techniques for Oncology

It is no secret that the rise of the Internet and other digital technologies has sparked renewed interest in AI-based techniques, especially those that fall under the umbrella of the subset of algorithms known as "Machine Learning" (ML). These advancements in electronics have allowed us to comprehend the world beyond the bounds of human cognition. A high-dimensional dataset's complicated nature. Although these techniques have been regularly employed by the medical sciences, their adoption to enhance patient care has been a bit slow. The availability of curated diverse data sets for model development is all examples of the substantial hurdles that have delayed these efforts. The future clinical acceptance of each of these characteristics may be affected by a number of limiting conditions, such as the time and resources spent on data collection and model development, the cost of integration relative to the time and resources spent on translation, and the potential for patient damage. In order to preserve value and enhance medical care, the goal of this article is to evaluate all facets of the issue in light of the validity of using ML methods in cancer, to serve as a template for further research and the subfield of oncology that serves as a model for other parts of the discipline

Electromyography Monitoring Systems in Rehabilitation: A Review of Clinical Applications, Wearable Devices and Signal Acquisition Methodologies

Recently, there has been an evolution toward a science-supported medicine, which uses replicable results from comprehensive studies to assist clinical decision-making. Reliable techniques are required to improve the consistency and replicability of studies assessing the effectiveness of clinical guidelines, mostly in muscular and therapeutic healthcare. In scientific research, surface electromyography (sEMG) is prevalent but underutilized as a valuable tool for physical medicine and rehabilitation. Other electrophysiological signals (e.g., from electrocardiogram (ECG), electroencephalogram (EEG), and needle EMG) are regularly monitored by medical specialists; nevertheless, the sEMG technique has not yet been effectively implemented in practical medical settings. However, sEMG has considerable clinical promise in evaluating muscle condition and operation; nevertheless, precise data extraction requires the definition of the procedures for tracking and interpreting sEMG and understanding the fundamental biophysics. This review is centered around the application of sEMG in rehabilitation and health monitoring systems, evaluating their technical specifications, including wearability. At first, this study examines methods and systems for tele-rehabilitation applications (i.e., neuromuscular, post-stroke, and sports) based on detecting EMG signals. Then, the fundamentals of EMG signal processing techniques and architectures commonly used to acquire and elaborate EMG signals are discussed. Afterward, a comprehensive and updated survey of wearable devices for sEMG detection, both reported in the scientific literature and on the market, is provided, mainly applied in rehabilitation training and physiological tracking. Discussions and comparisons about the examined solutions are presented to emphasize how rehabilitation professionals can reap the aid of neurobiological detection systems and identify perspectives in this field. These analyses contribute to identifying the key requirements of the next generation of wearable or portable sEMG devices employed in the healthcare field

Automated Detection of Left Bundle Branch Block from ECG Signal Utilizing the Maximal Overlap Discrete Wavelet Transform with ANFIS

Left bundle branch block (LBBB) is a common disorder in the heart’s electrical conduction system that leads to the ventricles’ uncoordinated contraction. The complete LBBB is usually associated with underlying heart failure and other cardiac diseases. Therefore, early automated detection is vital. This work aimed to detect the LBBB through the QRS electrocardiogram (ECG) complex segments taken from the MIT-BIH arrhythmia database. The used data contain 2655 LBBB (abnormal) and 1470 normal signals (i.e., 4125 total signals). The proposed method was employed in the following steps: (i) QRS segmentation and filtration, (ii) application of the Maximal Overlapped Discrete Wavelet Transform (MODWT) on the ECG R wave, (iii) selection of the detailed coefficients of the MODWT (D2, D3, D4), kurtosis, and skewness as extracted features to be fed into the Adaptive Neuro-Fuzzy Inference System (ANFIS) classifier. The obtained results proved that the proposed method performed well based on the achieved sensitivity, specificity, and classification accuracies of 99.81%, 100%, and 99.88%, respectively (F-Score is equal to 0.9990). Our results showed that the proposed method was robust and effective and could be used in real clinical situations

Social Media Devices’ Influence on User Neck Pain during the COVID-19 Pandemic: Collaborating Vertebral-GLCM Extracted Features with a Decision Tree

The prevalence of neck pain, a chronic musculoskeletal disease, has significantly increased due to the uncontrollable use of social media (SM) devices. The use of SM devices by younger generations increased enormously during the COVID-19 pandemic, being—in some cases—the only possibility for maintaining interpersonal, social, and friendship relationships. This study aimed to predict the occurrence of neck pain and its correlation with the intensive use of SM devices. It is based on nine quantitative parameters extracted from the retrospective X-ray images. The three parameters related to angle_1 (i.e., the angle between the global horizontal and the vector pointing from C7 vertebra to the occipito-cervical joint), angle_2 (i.e., the angle between the global horizontal and the vector pointing from C1 vertebra to the occipito-cervical joint), and the area between them were measured from the shape of the neck vertebrae, while the rest of the parameters were extracted from the images using the gray-level co-occurrence matrix (GLCM). In addition, the users’ ages and the duration of the SM usage (H.mean) were also considered. The decision tree (DT) machine-learning algorithm was employed to predict the abnormal cases (painful subjects) against the normal ones (no pain). The results showed that angle_1, area, and the image contrast significantly increased statistically with the time of SM-device usage, precisely in the range of 2 to 9 h. The DT showed a promising result demonstrated by classification accuracy and F1-scores of 94% and 0.95, respectively. Our findings confirmed that the objectively detected parameters, which elucidate the negative impacts of SM-device usage on neck pain, can be predicted by DT machine learning